Fulminant Pseudomembranous Colitis and Abdominal Compartment Syndrome

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Salvage immunotherapy for fulminant pseudomembranous colitis.

To cite: Abdulaziz S, AbouShala N, Al-Tarifi A, et al. BMJ Case Rep Published online: [please include Day Month Year] doi:10.1136/ bcr-2013-008786 DESCRIPTION A 49-year-old man was admitted to the intensive care unit (ICU) for septic shock secondary to Clostridium difficile infection (CDI) complicated with severe pseudomembranous colitis. His medical history was remarkable for glossectomy, prox...

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Fulminant colitis can be a sequelae of a number of conditions like Salmonellae, Shigella, E. Coli, Yersinia and other bacterial infections. Antibiotic associated pseudomembranous colitis is caused by clostridiuin difficle and can range from mild diarrhoea to fulminant colitis. Furthermore, chronic conditions like ulcerative colitis and Crohn’s disease can cause acute symptoms. Non-specific coli...

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Pseudomembranous colitis

In 1978, C. difficile was identified as the causative agent of pseudomembranous colitis [1]. There has been a worldwide increase in the incidence and severity of C. difficile-associated diarrhea (CDAD) due to increased use of broad-spectrum antimicrobial, crowded hospital wards [2,3] and/or poor infection control [4,5]. Pseudomembranous colitis associated with antibiotic use may alter the balan...

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Pseudomembranous Colitis

PMC has emerged, particularly in recent years, as a major and very expensive healthcare problem. Spores formed by the organism are implicated in spread of infection and have implications for hygiene and prevention of infection. C. difficile is an anaerobic Gram-positive rod which secretes two types of toxin (A and B), which cause disruption to the barrier function of the colonic mucosa. They ar...

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[Pseudomembranous colitis].

For some thirty years it has been known that pathologic proliferation oftoxigenic Clostridium difficile may lead to inflammation of colonic mucosa which, in its fully developed form, manifests as pseudomembranous colitis. CDAD (Clostridium difficile - Associated Disease or Diarrhoea) is the term which is generally and quite aptly used for the disease in literature on the subject. In most cases,...

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ژورنال

عنوان ژورنال: Pediatrics & Therapeutics

سال: 2016

ISSN: 2161-0665

DOI: 10.4172/2161-0665.1000285